Summary of the Third Annual Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling.

TitleSummary of the Third Annual Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling.
Publication TypeJournal Article
Year of Publication2020
AuthorsHolstein, SA, Al-Kadhimi, Z, Costa, LJ, Hahn, T, Hari, P, Hillengass, J, Jacob, A, Munshi, NC, Oliva, S, Pasquini, MC, Shi, Q, Stadtmauer, EA, Waldvogel, SL, McCarthy, PL
JournalBiol Blood Marrow Transplant
Volume26
Issue1
Paginatione7-e15
Date Published2020 01
ISSN1523-6536
KeywordsClinical Trials as Topic, Congresses as Topic, Education, Hematology, Humans, Multiple Myeloma, Neoplasm, Residual, Societies, Medical, United States
Abstract

The third annual Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling was held on November 29, 2018, at the American Society of Hematology (ASH) annual meeting. This workshop featured the latest research focused on minimal residual disease (MRD) assessment and immune profiling (IP) in myeloma as well as discussion of the statistical and regulatory issues intrinsic to the development of MRD as a surrogate endpoint. In this report, we provide a summary of the workshop and focus on the integration of MRD and IP assessment into trial design and clinical practice.

DOI10.1016/j.bbmt.2019.09.015
Alternate JournalBiol Blood Marrow Transplant
PubMed ID31526843
PubMed Central IDPMC6942175
Grant ListUG1 HL069286 / HL / NHLBI NIH HHS / United States
UG1 HL069249 / HL / NHLBI NIH HHS / United States
U01 HL069294 / HL / NHLBI NIH HHS / United States
R01 HL107213 / HL / NHLBI NIH HHS / United States
U24 CA076518 / CA / NCI NIH HHS / United States
U24 HL138660 / HL / NHLBI NIH HHS / United States